Antimicrobial Stewardship Program
Clinical Pathways
Antibiotic Catheter Locks
Antibiotic Desensitization
Several antibiotic desensitization protocol order forms have been developed by the
Antimicrobial Stewardship Program and Jill Poole, MD, and are approved for use at
The Nebraska Medical Center by the Antimicrobial Subcommittee, Pharmacy & Therapeutics
Committee, and Medical Executive Committee. The impetus for the development of these
forms was for use in the cystic fibrosis population, when antibiotic options are
often limited not only by allergies but also by resistance patterns. However, the
forms offer a convenient method of ordering antibiotic desensitization for other
patient populations as well.
A word of caution, antibiotic desensitization protocols do not eliminate the risk
of true anaphylaxis. Thus, antibiotic desensitization should only be considered
and utilized with caution and only when other alternatives have been exhausted.
Antibiotic desensitization protocols should only be performed in a monitored setting
in which resuscitative efforts could be immediately employed as needed.
Antimicrobial Surgical Prophylaxis
Clostridium difficile-associated Disease (CDAD)
Designated Units (those with a higher than normal incidence of CDAD as designted
by Healthcare Epidemiology)
General Population
Pneumonia Information
Sepsis Information
Soft Tissue Infections